Every day, your skin responds to sun, stress, and environment through a biological signaling network called the melanocortin system. It’s how skin produces melanin, defends against UV stress, and keeps inflammation in balance. Most skincare only sits on the surface. Chromelan™ works with this system directly, activating your skin’s own defense from within.

Portrait of a woman by calm water in soft daylight

Atlantic water meeting the shore from above

Meet Chromelan™.

Chromelan™ is a patented melanocortin peptide born from University of Arizona peptide research, one of the most respected melanocortin science programs in the world. It signals the receptors your skin already uses to create melanin, defend itself, and recover. The result is skin that doesn’t just look protected. It is biologically activated.

PatentedUniversity of Arizona research

How Chromelan™ works.

Connect.

Chromelan™ reaches the melanocortin receptors in the skin.

Signal.

It activates the skin’s own biological defense pathways.

Respond.

Skin produces natural melanin, strengthens its UV-stress defense, and calms inflammation.

Peptides don’t fail. Delivery fails.

Chromelan™ goes where it works, and stays there.

The barrier

Most peptides never make it past the skin’s surface. They sit on top, do nothing, and wash away.

The target

Chromelan™ penetrates into the epidermis, the layer where your melanin-producing cells and their receptors live.

The Neuvéra difference

Neuvéra formulations are engineered to deliver Chromelan™ to the receptor, so every application does real work.

Epidermis only

In human skin testing, Chromelan™ reached the epidermis and was not detected beyond it. Targeted to the skin, where it belongs.

Three pillars. One peptide.

Activate & Defend

Activates natural melanin production.
Healthy, sun-kissed tone without UV exposure.
Biological photoprotection and UV-stress defense.
Not a replacement for sunscreen.
Environmental resilience.

2.4xmore melanin in human skin testing

Calm & Repair

Anti-inflammatory.
Antimicrobial.
Supports skin experiencing redness and irritation.
Environmental damage repair.

0%irritation in a 21-day human study

Restore & Renew

Anti-aging.
Skin repair and recovery.
Barrier resilience.
Firmness and elasticity.
Refined texture and balanced tone.

86%showed measurable tone change in 21 days

Stones, linen and a skincare ritual in natural light

The proof is in the skin.

2.4x

more melanin.

In ex vivo human skin, Chromelan™ significantly increased melanin production in 7 days (p<0.001).

86%

Up to 86% of subjects.

In a 21-day human study, most subjects showed measurable skin tone change, with zero sun exposure, on fair skin, the hardest skin type to activate.

irritation.

No adverse reactions across the full human study. 100% of subjects found it pleasant to use.

Epidermis

Targeted delivery.

Chromelan™ penetrates to the epidermis, where it works, and was not detected beyond it.

Proprietary technology

Chromelan™ proprietary technology

University of Arizona Tech Launch Arizona

University of Arizona - Chromelan™ topicals are backed by 10 years of R&D and developed within the state-of-the-art laboratories, research facilities, and scientific expertise of University of Arizona Tech Launch Arizona

Chromelan™ finished formulas meet ISO 11930 international preservative efficacy standards.

Backed by world-class peptide scientists, including Dr. Victor J. Hruby, Ph.D., and Dr. Minying Cai, Ph.D., whose melanocortin research continues to be published in leading scientific journals.

10 years
Melanocortin peptide research and development at the University of Arizona.
2017
Ex vivo human skin testing: 2.4x more melanin in 7 days.
2018
Skin penetration testing: reaches the epidermis and is not detected beyond it.
2018 to 2019
21-day human study: measurable tone change in up to 86% of subjects, with 0% irritation.
2020
Finished formulas meet ISO 11930 preservative efficacy standards.
2023
Chromelan™ advisors publish new melanocortin peptide research in leading scientific journals.
Today
Chromelan™ launches as a patented ingredient for brands.

Download the Chromelan™ one-sheet

One peptide. Two outcomes.

In market today, inside Neuvéra’s PeptiPROTECT™ and PeptiLIFT™.

PeptiPROTECT™ Lotion

$69

Your daily biological defense.

Activates natural melanin for a healthy, sun-kissed tone while defending against UV stress and calming the skin.

Shop PeptiPROTECT™

PeptiLIFT™ Spray

$49

Visible renewal, powered by biology.

Supports firmness, elasticity, and refined texture for skin that looks lifted and resilient.

Shop PeptiLIFT™

Same patented peptide. Different formulations. That’s the power of a platform.

with

CHRMELAN^™

Look for the mark.

Brands that formulate with Chromelan™ carry this mark on pack, so customers know the patented peptide is inside. Neuvéra is the first.

NeuvéraPeptiPROTECT™, PeptiLIFT™

Defends and repairs. Not one or the other.

Collagen peptides and signal peptides rebuild structure in the dermis. Chromelan™ works through the skin’s own signaling to defend, repair, and renew.

Attribute	Chromelan™	Collagen peptides	Sederma Matrixyl™
How it works	Activates the skin’s own melanocortin signaling	Supplies collagen fragments, mostly taken orally	Signal peptide that mimics collagen fragments
Where it works	Epidermis	Dermis	Dermis
Format	Topical	Mostly oral supplements	Topical
Activates natural melanin	Yes	No	No
Photoprotection and UV-stress defense	Yes	No	No
Replaces sunscreen	No	No	No
Anti-inflammatory	Yes	Not a primary claim	Partial
Environmental damage repair	Yes	Not a primary claim	Photo-damage repair
Anti-aging	Yes	Yes	Yes
Patented	Yes	Some brands	Yes

Competitor information is based on publicly available materials. Matrixyl™ is a trademark of Sederma, part of Croda International. Chromelan™ is not affiliated with Sederma or Croda.

Chromelan™ is not a substitute for sunscreen or other sun-protection measures.

If it touches skin, Chromelan™ can power it.

Chromelan™ is an ingredient platform, not a single product.

Three ways to bring Chromelan™ to market.

Ingredient supply

Your formula. Powered by Chromelan™.

Who it’s for: Skincare brands and formulators looking for a patented, clinically studied active that competitors can’t buy off the shelf.
What you get: Patented Chromelan™ peptide, the technical data sheet, formulation guidance, and clinical data to support your claims.
How it works: Request the TDS → Sample and formulate → Launch.

Request the Technical Data Sheet

White label

Your brand. Our science. Skincare, done.

Who it’s for: Brands, clinics, and entrepreneurs who want a complete, market-ready Chromelan™ product without building a lab.
What you get: Custom formulation, manufacturing, and packaging support, with a patented active at the center.
How it works: Share your concept → We formulate and manufacture → You launch.

Start Your Product

Wholesale

Clinically studied skincare, ready for your shelves.

Who it’s for: Retailers, spas, med-spas, clinics, and wellness businesses.
What you get: PeptiPROTECT™ and PeptiLIFT™ at wholesale pricing, plus product education and marketing assets.
How it works: Apply → Get approved → Stock and sell.

Apply for Wholesale

For formulators

Active: Patented melanocortin receptor peptide
Molecular weight: 1530.77
Evaluated at: 20–100 ppm in gel and emulsion systems
Site of action: Epidermal level
Safety: Not classified as hazardous under EC 1272/2008
Full specifications: Technical Data Sheet

Why partner with Chromelan™.

Delivery engineeringWe built our company on one truth: delivery decides results.

Proprietary scienceA patented peptide your competitors can’t access.

Formulation expertiseFrom concept to finished product, built around Chromelan™.

Speed to marketA clear path from first conversation to launch.

Questions, answered.

What does Chromelan™ do?

Chromelan™ activates your skin’s natural defense system, supporting melanin production, UV-stress defense, and calmer, more resilient skin.

Is Chromelan™ a tanning peptide?

Chromelan™ activates natural melanin, which gives skin a healthy, sun-kissed tone. That same melanin is your skin’s built-in defense. And because Chromelan™ is topical and targeted to the epidermis, it works right where it’s applied.

How soon will I see results?

Chromelan™ builds real melanin, so tone develops gradually. Measurable changes appeared within 1 to 3 weeks of twice-daily use in human testing.

Is it suitable for sensitive skin?

In a 21-day human study, Chromelan™ produced zero irritation and no adverse reactions.

The future of skin is biological.

Build it with Chromelan™.

The patented peptide that activates your skin’s own defense.

One peptide. Four ways your brand wins.

Formulate

Build

Stock

Shop

Your skin has a defense system. Most skincare ignores it.